LPS Induces Occludin Dysregulation in Cerebral Microvascular Endothelial Cells via MAPK Signaling and Augmenting MMP-2 Levels

Disrupted blood-brain barrier (BBB) integrity contributes to cerebral edema during central nervous system infection. The current study explored the mechanism of lipopolysaccharide- (LPS-) induced dysregulation of tight junction (TJ) proteins. Human cerebral microvascular endothelial cells (hCMEC/D3)...

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Detalles Bibliográficos
Autores principales: Qin, Lan-hui, Huang, Wen, Mo, Xue-an, Chen, Yan-lan, Wu, Xiang-hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531183/
https://www.ncbi.nlm.nih.gov/pubmed/26290681
http://dx.doi.org/10.1155/2015/120641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531183/
https://www.ncbi.nlm.nih.gov/pubmed/26290681
http://dx.doi.org/10.1155/2015/120641

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