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Running rescues a fear-based contextual discrimination deficit in aged mice

Normal aging and exercise exert extensive, often opposing, effects on the dentate gyrus (DG) of the hippocampus altering volume, synaptic function, and behaviors. The DG is especially important for behaviors requiring pattern separation—a cognitive process that enables animals to differentiate betwe...

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Detalles Bibliográficos
Autores principales: Wu, Melody V., Luna, Victor M., Hen, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531235/
https://www.ncbi.nlm.nih.gov/pubmed/26321926
http://dx.doi.org/10.3389/fnsys.2015.00114