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Temperature-sensitive mutations for live-attenuated Rift Valley fever vaccines: implications from other RNA viruses

Rift Valley fever (RVF) is a mosquito-borne zoonotic disease endemic to the African continent. RVF is characterized by high rate of abortions in ruminants and hemorrhagic fever, encephalitis, or blindness in humans. RVF is caused by the Rift Valley fever virus (RVFV: genus Phlebovirus, family Bunyav...

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Detalles Bibliográficos
Autores principales: Nishiyama, Shoko, Ikegami, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531298/
https://www.ncbi.nlm.nih.gov/pubmed/26322023
http://dx.doi.org/10.3389/fmicb.2015.00787