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Temperature-sensitive mutations for live-attenuated Rift Valley fever vaccines: implications from other RNA viruses
Rift Valley fever (RVF) is a mosquito-borne zoonotic disease endemic to the African continent. RVF is characterized by high rate of abortions in ruminants and hemorrhagic fever, encephalitis, or blindness in humans. RVF is caused by the Rift Valley fever virus (RVFV: genus Phlebovirus, family Bunyav...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531298/ https://www.ncbi.nlm.nih.gov/pubmed/26322023 http://dx.doi.org/10.3389/fmicb.2015.00787 |