The antioxidant compound tert-butylhydroquinone activates Akt in myocardium, suppresses apoptosis and ameliorates pressure overload-induced cardiac dysfunction

Tert-butylhydroquinone (TBHQ) is an antioxidant compound which shows multiple cytoprotective actions. We evaluated the effects of TBHQ on pathological cardiac remodeling and dysfunction induced by chronic overload. Pressure overload was created by transverse aortic constriction (TAC) in male C57BL/6...

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Detalles Bibliográficos
Autores principales: Zhang, Yongtao, Fang Liu, Fang, Bi, Xiaolei, Wang, Shuangxi, Wu, Xiao, Jiang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531315/
https://www.ncbi.nlm.nih.gov/pubmed/26260024
http://dx.doi.org/10.1038/srep13005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531315/
https://www.ncbi.nlm.nih.gov/pubmed/26260024
http://dx.doi.org/10.1038/srep13005

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