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Splenic red pulp macrophages are intrinsically superparamagnetic and contaminate magnetic cell isolates

A main function of splenic red pulp macrophages is the degradation of damaged or aged erythrocytes. Here we show that these macrophages accumulate ferrimagnetic iron oxides that render them intrinsically superparamagnetic. Consequently, these cells routinely contaminate splenic cell isolates obtaine...

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Detalles Bibliográficos
Autores principales: Franken, Lars, Klein, Marika, Spasova, Marina, Elsukova, Anna, Wiedwald, Ulf, Welz, Meike, Knolle, Percy, Farle, Michael, Limmer, Andreas, Kurts, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531335/
https://www.ncbi.nlm.nih.gov/pubmed/26260698
http://dx.doi.org/10.1038/srep12940