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A critical role of Oct4A in mediating metastasis and disease-free survival in a mouse model of ovarian cancer

BACKGROUND: High grade epithelial ovarian cancer (EOC) is commonly characterised by widespread peritoneal dissemination and ascites. Metastatic EOC tumour cells can attach directly to neighbouring organs or alternatively, maintain long term tumourigenicity and chemoresistance by forming cellular agg...

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Detalles Bibliográficos
Autores principales: Samardzija, Chantel, Luwor, Rodney B, Volchek, Mila, Quinn, Michael A, Findlay, Jock K, Ahmed, Nuzhat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531496/
https://www.ncbi.nlm.nih.gov/pubmed/26260289
http://dx.doi.org/10.1186/s12943-015-0417-y