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A critical role of Oct4A in mediating metastasis and disease-free survival in a mouse model of ovarian cancer
BACKGROUND: High grade epithelial ovarian cancer (EOC) is commonly characterised by widespread peritoneal dissemination and ascites. Metastatic EOC tumour cells can attach directly to neighbouring organs or alternatively, maintain long term tumourigenicity and chemoresistance by forming cellular agg...
Autores principales: | Samardzija, Chantel, Luwor, Rodney B, Volchek, Mila, Quinn, Michael A, Findlay, Jock K, Ahmed, Nuzhat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531496/ https://www.ncbi.nlm.nih.gov/pubmed/26260289 http://dx.doi.org/10.1186/s12943-015-0417-y |
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