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Stochastic simulation of Boolean rxncon models: towards quantitative analysis of large signaling networks

BACKGROUND: Cellular decision-making is governed by molecular networks that are highly complex. An integrative understanding of these networks on a genome wide level is essential to understand cellular health and disease. In most cases however, such an understanding is beyond human comprehension and...

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Detalles Bibliográficos
Autores principales: Mori, Tomoya, Flöttmann, Max, Krantz, Marcus, Akutsu, Tatsuya, Klipp, Edda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531511/
https://www.ncbi.nlm.nih.gov/pubmed/26259567
http://dx.doi.org/10.1186/s12918-015-0193-8