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BRG1 overexpression in smooth muscle cells promotes the development of thoracic aortic dissection

BACKGROUND: Here we investigated Brahma-related gene 1 (BRG1) expression in aortic smooth muscle cells (SMCs) and its role in the regulation of the pathological changes in aortic SMCs of thoracic arotic dissection (TAD). METHODS: BRG1, matrix metalloproteinase 2 (MMP2), and MMP9 mRNA and protein exp...

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Detalles Bibliográficos
Autores principales: Yuan, Yang, Wang, Chong, Xu, Jibin, Tao, Jin, Xu, Zhiyun, Huang, Shengdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531522/
https://www.ncbi.nlm.nih.gov/pubmed/25304030
http://dx.doi.org/10.1186/1471-2261-14-144