Cargando…

BRG1 overexpression in smooth muscle cells promotes the development of thoracic aortic dissection

BACKGROUND: Here we investigated Brahma-related gene 1 (BRG1) expression in aortic smooth muscle cells (SMCs) and its role in the regulation of the pathological changes in aortic SMCs of thoracic arotic dissection (TAD). METHODS: BRG1, matrix metalloproteinase 2 (MMP2), and MMP9 mRNA and protein exp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Yang, Wang, Chong, Xu, Jibin, Tao, Jin, Xu, Zhiyun, Huang, Shengdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531522/ https://www.ncbi.nlm.nih.gov/pubmed/25304030 http://dx.doi.org/10.1186/1471-2261-14-144

Ejemplares similares

An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm
por: Lino Cardenas, Christian L., et al.
Publicado: (2018)

ER stress dependent microparticles derived from smooth muscle cells promote endothelial dysfunction during thoracic aortic aneurysm and dissection
por: Jia, Li-Xin, et al.
Publicado: (2017)

SPINT2 is involved in the proliferation, migration and phenotypic switching of aortic smooth muscle cells: Implications for the pathogenesis of thoracic aortic dissection
por: Li, Jun, et al.
Publicado: (2023)

The role of vascular smooth muscle cells in the development of aortic aneurysms and dissections
por: Rombouts, Karlijn B., et al.
Publicado: (2021)

Single-Cell RNA Sequencing Reveals Smooth Muscle Cells Heterogeneity in Experimental Aortic Dissection
por: Xu, Cheng, et al.
Publicado: (2022)

Post-Transcriptional Control of Tropoelastin in Aortic Smooth Muscle Cells Affects Aortic Dissection Onset
por: Qi, You-Fei, et al.
Publicado: (2018)

The cellular uncertainty in thoracic aortic dissections: the roles of METTL3 and NOTCH1 on m6A in human aortic smooth muscle cells
por: Wright, Kelly, et al.
Publicado: (2023)

A Functional Variant of SMAD4 Enhances Thoracic Aortic Aneurysm and Dissection Risk through Promoting Smooth Muscle Cell Apoptosis and Proteoglycan Degradation
por: Wang, Ying, et al.
Publicado: (2017)

Polycystin-1 Downregulation Induced Vascular Smooth Muscle Cells Phenotypic Alteration and Extracellular Matrix Remodeling in Thoracic Aortic Dissection
por: Zhang, Jing, et al.
Publicado: (2020)

Deletion of Socs3 Expression in Aortic Smooth Muscle Cells Ameliorates Aortic Dissection
por: Murphy, Michael P., et al.
Publicado: (2020)

Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms
por: Clément, Marc, et al.
Publicado: (2019)

Heterogeneity of Aortic Smooth Muscle Cells: A Determinant for Regional Characteristics of Thoracic Aortic Aneurysms?
por: Sawada, Hisashi, et al.
Publicado: (2018)

Complex Thoracic Aortic Dissection
por: Patel, Mihir, et al.
Publicado: (2014)

Phenotypic and Functional Changes of Endothelial and Smooth Muscle Cells in Thoracic Aortic Aneurysms
por: Malashicheva, Anna, et al.
Publicado: (2016)

Embryonic Heterogeneity of Smooth Muscle Cells in the Complex Mechanisms of Thoracic Aortic Aneurysms
por: Ito, Sohei, et al.
Publicado: (2022)

MED12 Regulates Smooth Muscle Cell Functions and Participates in the Development of Aortic Dissection
por: Zhou, Yingchao, et al.
Publicado: (2022)

Insulin Resistance Promotes the Formation of Aortic Dissection by Inducing the Phenotypic Switch of Vascular Smooth Muscle Cells
por: Zheng, Hui, et al.
Publicado: (2022)

Vascular Smooth Muscle FTO Promotes Aortic Dissecting Aneurysms via m6A Modification of Klf5
por: Ma, Dong, et al.
Publicado: (2020)

BRG1: Promoter or Suppressor of Cancer? The Outcome of BRG1’s Interaction with Specific Cellular Pathways
por: Shaykevich, Aaron, et al.
Publicado: (2023)

Chromatin regulation by Brg1 underlies heart muscle development and disease
por: Hang, Calvin T., et al.
Publicado: (2010)

Isolation and culture of smooth muscle cells from human acute type A aortic dissection
por: Lu, Shuyang, et al.
Publicado: (2013)

Redistribution of the chromatin remodeler Brg1 directs smooth muscle–derived adventitial progenitor–to–myofibroblast differentiation and vascular fibrosis
por: Jolly, Austin J., et al.
Publicado: (2023)

Dysregulation of interaction between LOX(high) fibroblast and smooth muscle cells contributes to the pathogenesis of aortic dissection
por: Chen, Yinan, et al.
Publicado: (2022)

Sirt3 Protects Against Thoracic Aortic Dissection Formation by Reducing Reactive Oxygen Species, Vascular Inflammation, and Apoptosis of Smooth Muscle Cells
por: Qiu, Lin, et al.
Publicado: (2021)

A Painless Thoracic Aortic Dissection
por: Mahmoud, Youssef, et al.
Publicado: (2016)

Risk Factors for Thoracic Aortic Dissection
por: Zhou, Zhen, et al.
Publicado: (2022)

Management of acute aortic dissection and thoracic aortic rupture
por: Fukui, Toshihiro
Publicado: (2018)

Thoracic Endovascular Aortic Repair for Acute Aortic Dissection
por: Uchida, Tetsuro, et al.
Publicado: (2018)

Thoracic Aortic Aneurysm and Factors Affecting Aortic Dissection
por: Chumachenko, Petr V., et al.
Publicado: (2020)

Genetic Deletion of Socs3 in Smooth Muscle Cells Ameliorates Aortic Dissection in Mice
por: Hirakata, Saki, et al.
Publicado: (2020)

Epigenetic control of vascular smooth muscle cells in Marfan and non-Marfan thoracic aortic aneurysms
por: Gomez, Delphine, et al.
Publicado: (2011)

Ciprofloxacin exacerbates dysfunction of smooth muscle cells in a microphysiological model of thoracic aortic aneurysm
por: Xiang, Bitao, et al.
Publicado: (2023)

EZH2 inhibits autophagic cell death of aortic vascular smooth muscle cells to affect aortic dissection
por: Li, Rui, et al.
Publicado: (2018)

miR‐145 attenuates phenotypic transformation of aortic vascular smooth muscle cells to prevent aortic dissection
por: Qiu, Zhi‐Huang, et al.
Publicado: (2021)

Association of Thoracic Aortic Aneurysm Versus Aortic Dissection on Outcomes After Thoracic Endovascular Aortic Repair
por: Hasan, Irsa S., et al.
Publicado: (2023)

Mechanisms of Smooth Muscle Cell Differentiation Are Distinctly Altered in Thoracic Aortic Aneurysms Associated with Bicuspid or Tricuspid Aortic Valves
por: Ignatieva, Elena, et al.
Publicado: (2017)

Adventitial Fibroblast Abormality in Thoracic Aortic Aneurysms and Aortic Dissections
por: Suh, Jong Hui, et al.
Publicado: (2011)

Multifunctional cationic nanosystems for nucleic acid therapy of thoracic aortic dissection
por: Xu, Chen, et al.
Publicado: (2019)

Gender differences in the dissection properties of ascending thoracic aortic aneurysms
por: Tong, Jianhua, et al.
Publicado: (2022)

Endovascular Stent in Traumatic Thoracic Aortic Dissection
por: Jang, Mi Ok, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_ogidd92lv7ls2d18s8en94h7l4