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Plk1 regulates MEK1/2 and proliferation in airway smooth muscle cells
BACKGROUND: Polo-like kinase 1 (Plk1) is a serine/threonine protein kinase that has been implicated in the regulation of mitosis. In addition, the activation of mitogen-activated protein kinase (MAPK) is a key event in the early stage of the growth factor response. The role of Plk1 in MAPK phosphory...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531535/ https://www.ncbi.nlm.nih.gov/pubmed/26242183 http://dx.doi.org/10.1186/s12931-015-0257-8 |