CoMEt: a statistical approach to identify combinations of mutually exclusive alterations in cancer

Cancer is a heterogeneous disease with different combinations of genetic alterations driving its development in different individuals. We introduce CoMEt, an algorithm to identify combinations of alterations that exhibit a pattern of mutual exclusivity across individuals, often observed for alterati...

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Detalles Bibliográficos
Autores principales: Leiserson, Mark DM, Wu, Hsin-Ta, Vandin, Fabio, Raphael, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531541/
https://www.ncbi.nlm.nih.gov/pubmed/26253137
http://dx.doi.org/10.1186/s13059-015-0700-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531541/
https://www.ncbi.nlm.nih.gov/pubmed/26253137
http://dx.doi.org/10.1186/s13059-015-0700-7

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