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CoMEt: a statistical approach to identify combinations of mutually exclusive alterations in cancer

Cancer is a heterogeneous disease with different combinations of genetic alterations driving its development in different individuals. We introduce CoMEt, an algorithm to identify combinations of alterations that exhibit a pattern of mutual exclusivity across individuals, often observed for alterati...

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Detalles Bibliográficos
Autores principales:	Leiserson, Mark DM, Wu, Hsin-Ta, Vandin, Fabio, Raphael, Benjamin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531541/ https://www.ncbi.nlm.nih.gov/pubmed/26253137 http://dx.doi.org/10.1186/s13059-015-0700-7

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