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Prognostic Significance of p21 and p53 Expression in Gastric Cancer

BACKGROUND : Cyclin-dependent kinase inhibitors (CDKI), including p21, p27 and p57 of the KIP family, are negative regulators of cell cycle progression and potentially act as tumor suppressors. The expression of p21 is induced by tumor suppressor gene p53. Mutations of p53 are common and found in va...

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Detalles Bibliográficos
Autores principales: Seo, Young-Ho, Joo, Young-Eun, Choi, Sung-Kyu, Rew, Jong-Sun, Park, Chang-Soo, Kim, Sei-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Internal Medicine 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531619/
https://www.ncbi.nlm.nih.gov/pubmed/12872447
http://dx.doi.org/10.3904/kjim.2003.18.2.98