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Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis

INTRODUCTION: Basal-like breast cancer (BLBC) is an aggressive subtype often characterized by distant metastasis, poor patient prognosis, and limited treatment options. Therefore, the discovery of alternative targets to restrain its metastatic potential is urgently needed. In this study, we aimed to...

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Detalles Bibliográficos
Autores principales: Papageorgis, Panagiotis, Ozturk, Sait, Lambert, Arthur W., Neophytou, Christiana M., Tzatsos, Alexandros, Wong, Chen K., Thiagalingam, Sam, Constantinou, Andreas I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531803/
https://www.ncbi.nlm.nih.gov/pubmed/26208975
http://dx.doi.org/10.1186/s13058-015-0607-y