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Acute exacerbations of COPD are associated with significant activation of matrix metalloproteinase 9 irrespectively of airway obstruction, emphysema and infection

BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (AE-COPD) are associated with accelerated aggravation of clinical symptoms and deterioration of pulmonary function. The mechanisms by which exacerbations may contribute to airway remodeling and declined lung function are poorly...

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Detalles Bibliográficos
Autores principales: Papakonstantinou, Eleni, Karakiulakis, George, Batzios, Spyros, Savic, Spasenija, Roth, Michael, Tamm, Michael, Stolz, Daiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531832/
https://www.ncbi.nlm.nih.gov/pubmed/26126526
http://dx.doi.org/10.1186/s12931-015-0240-4