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Acute exacerbations of COPD are associated with significant activation of matrix metalloproteinase 9 irrespectively of airway obstruction, emphysema and infection
BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (AE-COPD) are associated with accelerated aggravation of clinical symptoms and deterioration of pulmonary function. The mechanisms by which exacerbations may contribute to airway remodeling and declined lung function are poorly...
Autores principales: | Papakonstantinou, Eleni, Karakiulakis, George, Batzios, Spyros, Savic, Spasenija, Roth, Michael, Tamm, Michael, Stolz, Daiana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531832/ https://www.ncbi.nlm.nih.gov/pubmed/26126526 http://dx.doi.org/10.1186/s12931-015-0240-4 |
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