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Design of symmetric TIM barrel proteins from first principles

BACKGROUND: Computational protein design is a rapidly maturing field within structural biology, with the goal of designing proteins with custom structures and functions. Such proteins could find widespread medical and industrial applications. Here, we have adapted algorithms from the Rosetta softwar...

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Detalles Bibliográficos
Autores principales: Nagarajan, Deepesh, Deka, Geeta, Rao, Megha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531894/
https://www.ncbi.nlm.nih.gov/pubmed/26264284
http://dx.doi.org/10.1186/s12858-015-0047-4