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Design of symmetric TIM barrel proteins from first principles
BACKGROUND: Computational protein design is a rapidly maturing field within structural biology, with the goal of designing proteins with custom structures and functions. Such proteins could find widespread medical and industrial applications. Here, we have adapted algorithms from the Rosetta softwar...
Autores principales: | Nagarajan, Deepesh, Deka, Geeta, Rao, Megha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531894/ https://www.ncbi.nlm.nih.gov/pubmed/26264284 http://dx.doi.org/10.1186/s12858-015-0047-4 |
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