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The relationship between cisplatin-induced apoptosis and p53, bcl-2 and bax expression in human lung cancer cells
OBJECTIVES: Given the roles of bcl-2, bax and p53 in apoptosis, we investigated the effect of their expression on the response to cisplatin in order to understand the molecular events of cisplatin-resistance in lung cancers. METHODS: Three parental human lung cancer cell lines (PC9, PC14 and H69) an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Association of Internal Medicine
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531897/ https://www.ncbi.nlm.nih.gov/pubmed/10063313 http://dx.doi.org/10.3904/kjim.1999.14.1.42 |