Cargando…

Protective Effect of Chlormethiazole, a Sedative, against Acetaminophen-Induced Liver Injury in Mice

OBJECTIVES: The hepatotoxicity of acetaminophen is not a result of the parent compound but is mediated by its reactive metabolite N-acetyl-p-benzoquinone imine. Cytochrome P4502E1 (CYP2E1) is the principal enzyme of this biotransformation, which accounts for approximately 52% of the bioactivation in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Han Chu, Jung, Sung Ae, Jung, Hye Kyung, Yi, Sun Young, Kim, Doe Young, Moon, Il Hwan, Park, Sung Su
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Association of Internal Medicine 1999
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531924/ https://www.ncbi.nlm.nih.gov/pubmed/10461422 http://dx.doi.org/10.3904/kjim.1999.14.2.27

Ejemplares similares

Lysophosphatidic acid protects against acetaminophen-induced acute liver injury
por: Bae, Geon Ho, et al.
Publicado: (2017)

Effects of Gender and Menstrual Cycle on Colonic Transit Time in Healthy Subjects
por: Jung, Hye-Kyung, et al.
Publicado: (2003)

Red ginseng extract protects against carbon tetrachloride-induced liver fibrosis
por: Ki, Sung Hwan, et al.
Publicado: (2013)

Antioxidant effects of kimchi supplemented with black raspberry during fermentation protect against liver cirrhosis-induced oxidative stress in rats
por: Ryu, Eun-Hye, et al.
Publicado: (2019)

DDAH1 Protects against Acetaminophen-Induced Liver Hepatoxicity in Mice
por: Shen, Xiyue, et al.
Publicado: (2022)

Nuciferine Effectively Protects Mice against Acetaminophen-Induced Liver Injury
por: Zhou, Zixiong, et al.
Publicado: (2023)

Emerging Need for Vaccination against Hepatitis A Virus in Patients with Chronic Liver Disease in Korea
por: Song, Hyun Joo, et al.
Publicado: (2007)

Rutaecarpine Protects against Acetaminophen-Induced Acute Liver Injury in Mice by Activating Antioxidant Enzymes
por: Choi, Jae Ho, et al.
Publicado: (2021)

Bee Venom Phospholipase A2 Protects against Acetaminophen-Induced Acute Liver Injury by Modulating Regulatory T Cells and IL-10 in Mice
por: Kim, Hyunseong, et al.
Publicado: (2014)

Dietary saturated and monounsaturated fats protect against acute acetaminophen hepatotoxicity by altering fatty acid composition of liver microsomal membrane in rats
por: Hwang, Jinah, et al.
Publicado: (2011)

Auriculatone Sulfate Effectively Protects Mice Against Acetaminophen-Induced Liver Injury
por: Lin, Liangcai, et al.
Publicado: (2019)

Diallyl disulfide attenuates acetaminophen-induced renal injury in rats
por: Shin, Jin-Young, et al.
Publicado: (2016)

Hepatoprotective and Antioxidative Activities of Cornus officinalis against Acetaminophen-Induced Hepatotoxicity in Mice
por: Lee, Nam-Hun, et al.
Publicado: (2012)

Protective effects of (-)-epigallocatechin-3-gallate against acetaminophen-induced liver injury in rats)
por: Yao, Hsien-Tsung, et al.
Publicado: (2015)

Probiotic Bacillus Spores Protect Against Acetaminophen Induced Acute Liver Injury in Rats
por: Neag, Maria Adriana, et al.
Publicado: (2020)

Chronic treatment with acetaminophen protects against liver aging by targeting inflammation and oxidative stress
por: Brea, Rocío, et al.
Publicado: (2021)

Lumican, an Exerkine, Protects against Skeletal Muscle Loss
por: Cho, Han Jin, et al.
Publicado: (2022)

Caspase-3/7-mediated Cleavage of β2-spectrin is Required for Acetaminophen-induced Liver Damage
por: Baek, Hye Jung, et al.
Publicado: (2016)

Chitohexaose protects against acetaminophen-induced hepatotoxicity in mice
por: Barman, P K, et al.
Publicado: (2016)

Calcitriol Protects against Acetaminophen-Induced Hepatotoxicity in Mice
por: Sriphoosanaphan, Supachaya, et al.
Publicado: (2023)

Protective effects from Houttuynia cordata aqueous extract against acetaminophen-induced liver injury
por: Chen, Wei-ting, et al.
Publicado: (2014)

Enhanced autophagy contributes to protective effects of IL-22 against acetaminophen-induced liver injury
por: Mo, Ruidong, et al.
Publicado: (2018)

C-Reactive Protein Protects Against Acetaminophen-Induced Liver Injury by Preventing Complement Overactivation
por: Li, Hai-Yun, et al.
Publicado: (2021)

Paeoniflorin Protects against Acetaminophen-Induced Liver Injury in Mice via JNK Signaling Pathway
por: Deng, Xinyu, et al.
Publicado: (2022)

Liver-specific deletion of mechanistic target of rapamycin does not protect against acetaminophen-induced liver injury in mice
por: Sun, Hua, et al.
Publicado: (2021)

Allyl Isothiocyanate Protects Acetaminophen-Induced Liver Injury via NRF2 Activation by Decreasing Spontaneous Degradation in Hepatocyte
por: Kim, Min Woo, et al.
Publicado: (2020)

Cross-reactivity to Acetaminophen and Celecoxib According to the Type of Nonsteroidal Anti-inflammatory Drug Hypersensitivity
por: Kim, Yoon-Jeong, et al.
Publicado: (2014)

Bazhen Decoction Protects against Acetaminophen Induced Acute Liver Injury by Inhibiting Oxidative Stress, Inflammation and Apoptosis in Mice
por: Song, Erqun, et al.
Publicado: (2014)

Fast food diet-induced non-alcoholic fatty liver disease exerts early protective effect against acetaminophen intoxication in mice
por: Kim, Tae Hyung, et al.
Publicado: (2017)

NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice
por: Murray, Thomas V.A., et al.
Publicado: (2015)

BLT(1) signalling protects the liver against acetaminophen hepatotoxicity by preventing excessive accumulation of hepatic neutrophils
por: Kojo, Ken, et al.
Publicado: (2016)

The Significance of Sedation Control in Patients Receiving Mechanical Ventilation
por: Jung, Yun Jung, et al.
Publicado: (2012)

Sedation Regimens for Gastrointestinal Endoscopy
por: Moon, Sung-Hoon
Publicado: (2014)

Risk Factors for Predicting Hypoxia in Adult Patients Undergoing Bronchoscopy under Sedation
por: Choi, Ji Soo, et al.
Publicado: (2020)

Efficacy and Safety of Etomidate in Comparison with Propofol or Midazolam as Sedative for Upper Gastrointestinal Endoscopy
por: Kim, Jae Hyun, et al.
Publicado: (2020)

Montelukast Prevents Mice Against Acetaminophen-Induced Liver Injury
por: Pu, Shiyun, et al.
Publicado: (2019)

Kahweol Protects against Acetaminophen-Induced Hepatotoxicity in Mice through Inhibiting Oxidative Stress, Hepatocyte Death, and Inflammation
por: Kim, Jung-Yeon, et al.
Publicado: (2022)

CrebH protects against liver injury associated with colonic inflammation via modulation of exosomal miRNA
por: Lee, Sang-Hee, et al.
Publicado: (2023)

The Protective Effects of Imperatorin on Acetaminophen Overdose-Induced Acute Liver Injury
por: Gao, Zhao, et al.
Publicado: (2020)

The Protective Effect of Sonneratia apetala Fruit Extract on Acetaminophen-Induced Liver Injury in Mice
por: Liu, Jingjing, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_r0bcoi17cv7k1i6prchdltrqac