High-throughput virtual screening with e-pharmacophore and molecular simulations study in the designing of pancreatic lipase inhibitors

BACKGROUND: Obesity is a progressive metabolic disorder in the current world population, and is characterized by the excess deposition of fat in the adipose tissue. Pancreatic lipase is one of the key enzymes in the hydrolysis of triglycerides into monoglycerides and free fatty acids, and is thus co...

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Detalles Bibliográficos
Autores principales: Veeramachaneni, Ganesh Kumar, Raj, K Kranthi, Chalasani, Leela Madhuri, Bondili, Jayakumar Singh, Talluri, Venkateswara Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532172/
https://www.ncbi.nlm.nih.gov/pubmed/26273199
http://dx.doi.org/10.2147/DDDT.S84052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532172/
https://www.ncbi.nlm.nih.gov/pubmed/26273199
http://dx.doi.org/10.2147/DDDT.S84052

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