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Kinase inhibitor screening identifies CDK4 as a potential therapeutic target for melanoma
Despite recent advances in targeted therapies and immunotherapies metastatic melanoma remains only rarely curable. The objective of the present study was to identify novel therapeutic targets for metastatic melanoma. A library of 160 well-characterised and potent protein kinase inhibitors was screen...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532220/ https://www.ncbi.nlm.nih.gov/pubmed/26201960 http://dx.doi.org/10.3892/ijo.2015.3097 |