1,25-Dihydroxyvitamin D(3) attenuates endotoxin-induced production of inflammatory mediators by inhibiting MAPK activation in primary cortical neuron-glia cultures

BACKGROUND: Neuroinflammation occurs in insulted regions of the brain and may be due to reactive oxygen species (ROS), nitric oxide (NO), cytokines, and chemokines produced by activated glia. Excessive production of neurotoxic molecules causes further neuronal damage. Low levels of vitamin D(3) are...

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Detalles Bibliográficos
Autores principales: Huang, Ya-Ni, Ho, Yi-Jung, Lai, Chien-Cheng, Chiu, Chien-Tsai, Wang, Jia-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532256/
https://www.ncbi.nlm.nih.gov/pubmed/26259787
http://dx.doi.org/10.1186/s12974-015-0370-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532256/
https://www.ncbi.nlm.nih.gov/pubmed/26259787
http://dx.doi.org/10.1186/s12974-015-0370-0

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