Characterization of preclinical in vitro and in vivo pharmacokinetics properties for KBP-7018, a new tyrosine kinase inhibitor candidate for treatment of idiopathic pulmonary fibrosis

KBP-7018 is a novel selective tyrosine kinase inhibitor with potential for the treatment of idiopathic pulmonary fibrosis. The objective of this study was to characterize the preclinical pharmacokinetics of KBP-7018 in vitro and in vivo, and then to assess the likelihood of developing KBP-7018 as a...

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Detalles Bibliográficos
Autores principales: Huang, Zhenhua, Li, Heran, Zhang, Qian, Tan, Xiaojuan, Lu, Fangzheng, Liu, Hongzhuo, Li, Sanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532346/
https://www.ncbi.nlm.nih.gov/pubmed/26273193
http://dx.doi.org/10.2147/DDDT.S83055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532346/
https://www.ncbi.nlm.nih.gov/pubmed/26273193
http://dx.doi.org/10.2147/DDDT.S83055

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