Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer

General activation of hypoxia-inducible factor (HIF) pathways is classically associated with adverse prognosis in cancer and has been proposed to contribute to oncogenic drive. In clear cell renal carcinoma (CCRC) HIF pathways are upregulated by inactivation of the von-Hippel-Lindau tumor suppressor...

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Detalles Bibliográficos
Autores principales: Salama, Rafik, Masson, Norma, Simpson, Peter, Sciesielski, Lina Katrin, Sun, Min, Tian, Ya-Min, Ratcliffe, Peter John, Mole, David Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532367/
https://www.ncbi.nlm.nih.gov/pubmed/26262842
http://dx.doi.org/10.1371/journal.pone.0134645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532367/
https://www.ncbi.nlm.nih.gov/pubmed/26262842
http://dx.doi.org/10.1371/journal.pone.0134645

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