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Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation

Mesenchymal stem cell (MSC) differentiation is regulated by the extracellular matrix (ECM) through activation of intracellular signaling mediators. The stiffness of the ECM was shown to be an important regulatory factor for MSC differentiation, and transcriptional coactivator with PDZ-binding motif...

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Detalles Bibliográficos
Autores principales: Hwang, Jun-Ha, Byun, Mi Ran, Kim, A. Rum, Kim, Kyung Min, Cho, Hang Jun, Lee, Yo Han, Kim, Juwon, Jeong, Mi Gyeong, Hwang, Eun Sook, Hong, Jeong-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532446/
https://www.ncbi.nlm.nih.gov/pubmed/26262877
http://dx.doi.org/10.1371/journal.pone.0135519