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Extensive White Matter Alterations and Its Correlations with Ataxia Severity in SCA 2 Patients

BACKGROUND: Previous studies of SCA2 have revealed significant degeneration of white matter tracts in cerebellar and cerebral regions. The motor deficit in these patients may be attributable to the degradation of projection fibers associated with the underlying neurodegenerative process. However, th...

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Detalles Bibliográficos
Autores principales: Hernandez-Castillo, Carlos R., Galvez, Victor, Mercadillo, Roberto, Diaz, Rosalinda, Campos-Romo, Aurelio, Fernandez-Ruiz, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532454/
https://www.ncbi.nlm.nih.gov/pubmed/26263162
http://dx.doi.org/10.1371/journal.pone.0135449