The Role of MKP-1 in the Anti-Proliferative Effects of Glucocorticoids in Primary Rat Pre-Osteoblasts

Glucocorticoid (GC)-induced osteoporosis has been attributed to a GC-induced suppression of pre-osteoblast proliferation. Our previous work identified a critical role for mitogen-activated protein kinase (MAPK) phosphatase-1 (MKP-1) in mediating the anti-proliferative effects of GCs in immortalized...

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Detalles Bibliográficos
Autores principales: Sanderson, Micheline, Sadie-Van Gijsen, Hanél, Hough, Stephen, Ferris, William F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532462/
https://www.ncbi.nlm.nih.gov/pubmed/26263165
http://dx.doi.org/10.1371/journal.pone.0135358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532462/
https://www.ncbi.nlm.nih.gov/pubmed/26263165
http://dx.doi.org/10.1371/journal.pone.0135358

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