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KSHV MicroRNAs Repress Tropomyosin 1 and Increase Anchorage-Independent Growth and Endothelial Tube Formation

Kaposi’s sarcoma (KS) is characterized by highly vascularized spindle-cell tumors induced after infection of endothelial cells by Kaposi’s sarcoma-associated herpesvirus (KSHV). In KS tumors, KSHV expresses only a few latent proteins together with 12 pre-microRNAs. Previous microarray and proteomic...

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Detalles Bibliográficos
Autores principales: Kieffer-Kwon, Philippe, Happel, Christine, Uldrick, Thomas S., Ramalingam, Dhivya, Ziegelbauer, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532463/
https://www.ncbi.nlm.nih.gov/pubmed/26263384
http://dx.doi.org/10.1371/journal.pone.0135560