Scriptaid Treatment Decreases DNA Methyltransferase 1 Expression by Induction of MicroRNA-152 Expression in Porcine Somatic Cell Nuclear Transfer Embryos

Abnormal epigenetic reprogramming of donor nuclei after somatic cell nuclear transfer (SCNT) is thought to be the main cause of low cloning efficiencies. A growing body of evidence has demonstrated a positive role of Scriptaid, a histone deacetylase inhibitor (HDACi) that belongs to an existing clas...

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Detalles Bibliográficos
Autores principales: Liang, Shuang, Zhao, Ming-Hui, Choi, Jeong-woo, Kim, Nam-Hyung, Cui, Xiang-Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532471/
https://www.ncbi.nlm.nih.gov/pubmed/26261994
http://dx.doi.org/10.1371/journal.pone.0134567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532471/
https://www.ncbi.nlm.nih.gov/pubmed/26261994
http://dx.doi.org/10.1371/journal.pone.0134567

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