Promoter Hypomethylation of Maspin Inhibits Migration and Invasion of Extravillous Trophoblast Cells during Placentation

OBJECTIVE: Extravillous trophoblast (EVT) cells invade the endometrium and the maternal spiral arterioles during the first trimester. Mammary Serine Protease Inhibitor (Maspin, SERPINB5) plays a putative role in regulating the invasive activity of cytotrophoblasts. The maspin gene is silenced in var...

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Detalles Bibliográficos
Autores principales: Shi, Xinwei, Liu, Hao, Cao, Jing, Liu, Qing, Tang, Guiju, Liu, Wanlu, Liu, Haiyi, Deng, Dongrui, Qiao, Fuyuan, Wu, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532475/
https://www.ncbi.nlm.nih.gov/pubmed/26263377
http://dx.doi.org/10.1371/journal.pone.0135359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532475/
https://www.ncbi.nlm.nih.gov/pubmed/26263377
http://dx.doi.org/10.1371/journal.pone.0135359

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