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Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice

Alterations in lipid metabolism have been found in several neurodegenerative disorders, including Alzheimer’s disease. Lipoprotein lipase (LPL) hydrolyzes triacylglycerides in lipoproteins and regulates lipid metabolism in multiple organs and tissues, including the central nervous system (CNS). Thou...

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Detalles Bibliográficos
Autores principales: Yu, Tian, Taussig, Matthew D., DiPatrizio, Nicholas V., Astarita, Giuseppe, Piomelli, Daniele, Bergman, Bryan C., Dell’Acqua, Mark L., Eckel, Robert H., Wang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532501/
https://www.ncbi.nlm.nih.gov/pubmed/26263173
http://dx.doi.org/10.1371/journal.pone.0135113