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Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice
Alterations in lipid metabolism have been found in several neurodegenerative disorders, including Alzheimer’s disease. Lipoprotein lipase (LPL) hydrolyzes triacylglycerides in lipoproteins and regulates lipid metabolism in multiple organs and tissues, including the central nervous system (CNS). Thou...
Autores principales: | Yu, Tian, Taussig, Matthew D., DiPatrizio, Nicholas V., Astarita, Giuseppe, Piomelli, Daniele, Bergman, Bryan C., Dell’Acqua, Mark L., Eckel, Robert H., Wang, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532501/ https://www.ncbi.nlm.nih.gov/pubmed/26263173 http://dx.doi.org/10.1371/journal.pone.0135113 |
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