Chemokine-Targeted Mouse Models of Human Primary and Metastatic Colorectal Cancer

Current orthotopic xenograft models of human colorectal cancer (CRC) require surgery and do not robustly form metastases in the liver, the most common site clinically. CCR9 traffics lymphocytes to intestine and colorectum. We engineered use of the chemokine receptor CCR9 in CRC cell lines and patien...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Huanhuan Joyce, Sun, Jian, Huang, Zhiliang, Hou, Harry, Arcilla, Myra, Rakhilin, Nikolai, Joe, Daniel J., Choi, Jiahn, Gadamsetty, Poornima, Milsom, Jeff, Nandakumar, Govind, Longman, Randy, Zhou, Xi Kathy, Edwards, Robert, Chen, Jonlin, Chen, Kai Yuan, Bu, Pengcheng, Wang, Lihua, Xu, Yitian, Munroe, Robert, Abratte, Christian, Miller, Andrew D., Gümüş, Zeynep H., Shuler, Michael, Nishimura, Nozomi, Edelmann, Winfried, Shen, Xiling, Lipkin, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532544/
https://www.ncbi.nlm.nih.gov/pubmed/26006007
http://dx.doi.org/10.1038/nbt.3239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532544/
https://www.ncbi.nlm.nih.gov/pubmed/26006007
http://dx.doi.org/10.1038/nbt.3239

Ejemplares similares