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Singlet oxygen treatment of tumor cells triggers extracellular singlet oxygen generation, catalase inactivation and reactivation of intercellular apoptosis-inducing signaling()

Intracellular singlet oxygen generation in photofrin-loaded cells caused cell death without discrimination between nonmalignant and malignant cells. In contrast, extracellular singlet oxygen generation caused apoptosis induction selectively in tumor cells through singlet oxygen-mediated inactivation...

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Detalles Bibliográficos
Autores principales: Riethmüller, Michaela, Burger, Nils, Bauer, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532730/
https://www.ncbi.nlm.nih.gov/pubmed/26225731
http://dx.doi.org/10.1016/j.redox.2015.07.006