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Cocaine Causes Apoptotic Death in Rat Mesencephalon and Striatum Primary Cultures

To study cocaine's toxic effects in vitro, we have used primary mesencephalic and striatal cultures from rat embryonic brain. Treatment with cocaine causes a dramatic increase in DNA fragmentation in both primary cultures. The toxicity induced by cocaine was paralleled with a concomitant decrea...

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Detalles Bibliográficos
Autores principales: Lepsch, Lucilia B., Planeta, Cleopatra S., Scavone, Critoforo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532811/
https://www.ncbi.nlm.nih.gov/pubmed/26295051
http://dx.doi.org/10.1155/2015/750752