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Cocaine Causes Apoptotic Death in Rat Mesencephalon and Striatum Primary Cultures
To study cocaine's toxic effects in vitro, we have used primary mesencephalic and striatal cultures from rat embryonic brain. Treatment with cocaine causes a dramatic increase in DNA fragmentation in both primary cultures. The toxicity induced by cocaine was paralleled with a concomitant decrea...
Autores principales: | Lepsch, Lucilia B., Planeta, Cleopatra S., Scavone, Critoforo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532811/ https://www.ncbi.nlm.nih.gov/pubmed/26295051 http://dx.doi.org/10.1155/2015/750752 |
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