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The mechanochemistry of copper reports on the directionality of unfolding in model cupredoxin proteins
Understanding the directionality and sequence of protein unfolding is crucial to elucidate the underlying folding free energy landscape. An extra layer of complexity is added in metalloproteins, where a metal cofactor participates in the correct, functional fold of the protein. However, the precise...
Autores principales: | Beedle, Amy E. M., Lezamiz, Ainhoa, Stirnemann, Guillaume, Garcia-Manyes, Sergi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532836/ https://www.ncbi.nlm.nih.gov/pubmed/26235284 http://dx.doi.org/10.1038/ncomms8894 |
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