Harmonic force spectroscopy measures load-dependent kinetics of individual human β-cardiac myosin molecules

Molecular motors are responsible for numerous cellular processes from cargo transport to heart contraction. Their interactions with other cellular components are often transient and exhibit kinetics that depend on load. Here, we measure such interactions using ‘harmonic force spectroscopy'. In...

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Detalles Bibliográficos
Autores principales: Sung, Jongmin, Nag, Suman, Mortensen, Kim I., Vestergaard, Christian L., Sutton, Shirley, Ruppel, Kathleen, Flyvbjerg, Henrik, Spudich, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532873/
https://www.ncbi.nlm.nih.gov/pubmed/26239258
http://dx.doi.org/10.1038/ncomms8931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532873/
https://www.ncbi.nlm.nih.gov/pubmed/26239258
http://dx.doi.org/10.1038/ncomms8931

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