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Quantitative interactome analysis reveals a chemoresistant edgotype

Chemoresistance is a common mode of therapy failure for many cancers. Tumours develop resistance to chemotherapeutics through a variety of mechanisms, with proteins serving pivotal roles. Changes in protein conformations and interactions affect the cellular response to environmental conditions contr...

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Detalles Bibliográficos
Autores principales: Chavez, Juan D., Schweppe, Devin K., Eng, Jimmy K., Zheng, Chunxiang, Taipale, Alex, Zhang, Yiyi, Takara, Kohji, Bruce, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532879/
https://www.ncbi.nlm.nih.gov/pubmed/26235782
http://dx.doi.org/10.1038/ncomms8928