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Quantitative interactome analysis reveals a chemoresistant edgotype
Chemoresistance is a common mode of therapy failure for many cancers. Tumours develop resistance to chemotherapeutics through a variety of mechanisms, with proteins serving pivotal roles. Changes in protein conformations and interactions affect the cellular response to environmental conditions contr...
Autores principales: | Chavez, Juan D., Schweppe, Devin K., Eng, Jimmy K., Zheng, Chunxiang, Taipale, Alex, Zhang, Yiyi, Takara, Kohji, Bruce, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532879/ https://www.ncbi.nlm.nih.gov/pubmed/26235782 http://dx.doi.org/10.1038/ncomms8928 |
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