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Mammalian synthetic circuits with RNA binding proteins delivered by RNA

Synthetic regulatory circuits encoded on RNA rather than DNA could provide a means to control cell behavior while avoiding potentially harmful genomic integration in therapeutic applications. We create post-transcriptional circuits using RNA-binding proteins, which can be wired in a plug-and-play fa...

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Detalles Bibliográficos
Autores principales: Wroblewska, Liliana, Kitada, Tasuku, Endo, Kei, Siciliano, Velia, Stillo, Breanna, Saito, Hirohide, Weiss, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532950/
https://www.ncbi.nlm.nih.gov/pubmed/26237515
http://dx.doi.org/10.1038/nbt.3301