Estrogen sulfotransferase ablation sensitizes mice to sepsis

Sepsis is the host's deleterious systemic inflammatory response to microbial infections. Here we report an essential role for the estrogen sulfotransferase (EST or SULT1E1), a conjugating enzyme that sulfonates and deactivates estrogens, in sepsis response. Both the cecal ligation and puncture...

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Detalles Bibliográficos
Autores principales: Chai, Xiaojuan, Guo, Yan, Jiang, Mengxi, Hu, Bingfang, Li, Zhigang, Fan, Jie, Deng, Meihong, Billiar, Timothy R., Kucera, Heidi, Gaikwad, Nilesh W., Xu, Meishu, Lu, Peipei, Yan, Jiong, Fu, Haiyan, Liu, Youhua, Yu, Lushan, Huang, Min, Zeng, Su, Xie, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532951/
https://www.ncbi.nlm.nih.gov/pubmed/26259151
http://dx.doi.org/10.1038/ncomms8979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532951/
https://www.ncbi.nlm.nih.gov/pubmed/26259151
http://dx.doi.org/10.1038/ncomms8979

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