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Enhancer additivity and non-additivity are determined by enhancer strength in the Drosophila embryo

Metazoan genes are embedded in a rich milieu of regulatory information that often includes multiple enhancers possessing overlapping activities. In this study, we employ quantitative live imaging methods to assess the function of pairs of primary and shadow enhancers in the regulation of key pattern...

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Detalles Bibliográficos
Autores principales: Bothma, Jacques P, Garcia, Hernan G, Ng, Samuel, Perry, Michael W, Gregor, Thomas, Levine, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532966/
https://www.ncbi.nlm.nih.gov/pubmed/26267217
http://dx.doi.org/10.7554/eLife.07956