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Enhancer additivity and non-additivity are determined by enhancer strength in the Drosophila embryo
Metazoan genes are embedded in a rich milieu of regulatory information that often includes multiple enhancers possessing overlapping activities. In this study, we employ quantitative live imaging methods to assess the function of pairs of primary and shadow enhancers in the regulation of key pattern...
Autores principales: | Bothma, Jacques P, Garcia, Hernan G, Ng, Samuel, Perry, Michael W, Gregor, Thomas, Levine, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532966/ https://www.ncbi.nlm.nih.gov/pubmed/26267217 http://dx.doi.org/10.7554/eLife.07956 |
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