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Arsenic Trioxide Activate Transcription of Heme Oxygenase-1 by Promoting Nuclear Translocation of NFE2L2

In a previous study, we found that induced expression of Heme Oxygenase-1 (HO-1) is responsible for the resistance of human osteosarcoma MG63 cells to the chemotherapeutic agent arsenic trioxide (ATO). The present study was aimed at investigating the molecular mechanisms underlying the induction of...

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Detalles Bibliográficos
Autores principales: Yue, Zhen, Zhong, Lingzhi, Mou, Yan, Wang, Xiaotong, Zhang, Haiying, Wang, Yang, Xia, Jianxin, Li, Ronggui, Wang, Zonggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532976/
https://www.ncbi.nlm.nih.gov/pubmed/26283888
http://dx.doi.org/10.7150/ijms.12450