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Vasculature Disruption Enhances Bacterial Targeting of Autochthonous Tumors

Attenuated Salmonella enterica serovar Typhimurium (S. Typhimurium) has been developed as a vector to deliver therapeutic agents to tumors. The potential of S. Typhimurium in cancer therapy is largely due to its reported propensity to accumulate at greater than 1,000-fold higher concentrations in tu...

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Detalles Bibliográficos
Autores principales: Drees, Jeremy J., Mertensotto, Michael J., Augustin, Lance B., Schottel, Janet L., Saltzman, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532981/
https://www.ncbi.nlm.nih.gov/pubmed/26284135
http://dx.doi.org/10.7150/jca.12491