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Inhibition of ZEB1 expression induces redifferentiation of adult human β cells expanded in vitro

In-vitro expansion of functional adult human β-cells is an attractive approach for generating insulin-producing cells for transplantation. However, human islet cell expansion in culture results in loss of β-cell phenotype and epithelial-mesenchymal transition (EMT). This process activates expression...

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Detalles Bibliográficos
Autores principales:	Sintov, Elad, Nathan, Gili, Knoller, Sarah, Pasmanik-Chor, Metsada, Russ, Holger A., Efrat, Shimon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532995/ https://www.ncbi.nlm.nih.gov/pubmed/26264186 http://dx.doi.org/10.1038/srep13024

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