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Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation

Here, we investigated the anticancer effect of Rhus coriaria on three breast cancer cell lines. We demonstrated that Rhus coriaria ethanolic extract (RCE) inhibits the proliferation of these cell lines in a time- and concentration-dependent manner. RCE induced senescence and cell cycle arrest at G1...

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Detalles Bibliográficos
Autores principales: El Hasasna, Hussain, Athamneh, Khawlah, Al Samri, Halima, Karuvantevida, Noushad, Al Dhaheri, Yusra, Hisaindee, Soleiman, Ramadan, Gaber, Al Tamimi, Nedaa, AbuQamar, Synan, Eid, Ali, Iratni, Rabah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532997/
https://www.ncbi.nlm.nih.gov/pubmed/26263881
http://dx.doi.org/10.1038/srep13013